Pharmaceutical dimethicone is polydimethylsiloxane qualified to a pharmacopeia and selected by grade and nominal viscosity. The Ph.Eur./BP Dimeticone monograph defines 20, 350 and 1000 cSt nominal grades; the 350 grade is the common skin protectant and topical excipient. USP-NF Dimethicone is also available. RawSource supplies the pharmacopeial grade and viscosity your formulation requires, sourced to spec.
Grade selection — Pharmacopeial grade x nominal viscosity
Pharmaceutical dimethicone is polydimethylsiloxane qualified to a pharmacopeia. The European Pharmacopoeia / British Pharmacopoeia Dimeticone monograph specifies nominal viscosity grades — 20, 350 and 1000 mm2/s (cSt); the USP-NF lists Dimethicone separately. The selection axis is the pharmacopeial grade plus the nominal viscosity matched to the dosage form.
| Pharmacopeial grade x nominal viscosity | Nominal viscosity | Pharmacopeia | Typical applications | Supply |
|---|---|---|---|---|
| Dimeticone 20 (Ph.Eur. / BP) | 20 cSt | Ph.Eur. / BP | low-viscosity excipient and antifoam base for oral and topical preparations | sourced-to-spec |
| Dimeticone 350 (Ph.Eur. / BP) | 350 cSt | Ph.Eur. / BP | skin protectant and barrier creams; the common topical excipient grade | sourced-to-spec |
| Dimeticone 1000 (Ph.Eur. / BP) | 1000 cSt | Ph.Eur. / BP | high-viscosity barrier protectant and personal lubricant base | sourced-to-spec |
| Dimethicone (USP-NF) | — | USP-NF | US-pharmacopeial dimethicone for topical and excipient use (nominal viscosity confirmed per CoA) | sourced-to-spec |
Frequently Asked Questions
What viscosity grades does pharmaceutical dimethicone come in?
The European Pharmacopoeia and British Pharmacopoeia Dimeticone monograph specifies nominal grades of 20, 350 and 1000 cSt. The 350 grade is the common skin-protectant and topical excipient; the 20 grade is a low-viscosity excipient and antifoam base; the 1000 grade is a high-viscosity barrier and lubricant base.
Is this Ph.Eur./BP or USP grade?
Both are available. Pharmaceutical dimethicone is selected by pharmacopeia: Dimeticone to Ph.Eur./BP (nominal 20/350/1000 cSt) or Dimethicone to USP-NF. We supply to the pharmacopeia your formulation requires, with a grade-specific CoA and SDS on every order.
What CAS number is pharmaceutical dimethicone?
Dimethicone (Dimeticone) is CAS 9006-65-9, with polymer mixtures also listed under 63148-62-9. It is a polymer family, so the page is organised by pharmacopeial grade and nominal viscosity rather than a single fixed property set.