Specialty Additives Available to Source

Isotretinoin

CAS 4759-48-2 · MF C20H28O2 · MW 300.4 g/mol

A potent oral retinoid used to treat severe acne by reducing sebum production, unclogging pores, and preventing breakouts. Commonly prescribed for persistent

SDS / TDS Download
CAS Number
4759-48-2
Molecular Formula
C20H28O2
Molecular Weight
300.4 g/mol
Material Family
Specialty Additives
Functional Roles
Physical Properties
melting_point
372 to 374 u00b0F (NTP, 1992)
boiling_point
462.8
solubility
less than 1 mg/mL at 72 u00b0F (NTP, 1992)
GHS / SDS Safety Danger
Environmental Hazard Irritant Health Hazard
  • H315: Causes skin irritation [Warning Skin corrosion/irritation]
  • H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
  • H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]
  • H315 (30.7%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H410 (71.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
  • H400 (71.2%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
  • H360: May damage fertility or the unborn child [Danger Reproductive toxicity]
  • H319 (31.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (30.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
  • H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Chemical Identity
CAS Number4759-48-2
IUPAC Name(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
InChI KeySHGAZHPCJJPHSC-XFYACQKRSA-N
PubChem CID 5282379
INCI NameCIS-RETINOIC ACID
Synonyms & Trade Names
Isotretinoin 13-cis-Retinoic acid Accutane 13-cis-Vitamin A acid Neovitamin A acid Claravis Roaccutane Amnesteem 13-cis retinoic acid Isotrex Sotret Isotretinoine Roaccutan Teriosal isotretinoino
Full Description

A potent oral retinoid used to treat severe acne by reducing sebum production, unclogging pores, and preventing breakouts. Commonly prescribed for persistent