Silanes & Organosilanes Available to Source

Mercaptopropyltrimethoxysilane

MPTMS
CAS 4420-74-0 · MF C6H16O3SSi · MW 196.34 g/mol

Mercaptopropyltrimethoxysilane (MPTMS) is an organosilane coupling agent with the molecular formula C6H16O3SSi that provides adhesion promotion and coupling functionality between organic and inorganic materials. This silane compound is utilized across agriculture, coatings & construction, industrial manufacturing, and plastics & polymers industries where enhanced interfacial bonding is required. The mercapto functional…

SDS / TDS Download
CAS Number
4420-74-0
Molecular Formula
C6H16O3SSi
Molecular Weight
196.34 g/mol
Material Family
Silanes & Organosilanes
Functional Roles
GHS / SDS Safety Warning
Environmental Hazard Irritant
  • H317 (71.7%): May cause an allergic skin reaction [Warning Sensitization, Skin]
  • H411 (64.7%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
  • H302 (94%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (12.5%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H319 (10.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Chemical Identity
CAS Number4420-74-0
IUPAC Name3-trimethoxysilylpropane-1-thiol
InChI KeyUUEWCQRISZBELL-UHFFFAOYSA-N
PubChem CID 20473
INCI NameMERCAPTOPROPYLTRIMETHOXYSILANE
Synonyms & Trade Names
(3-Mercaptopropyl)trimethoxysilane 3-Mercaptopropyltrimethoxysilane 3-(Trimethoxysilyl)propanethiol 1-Propanethiol, 3-(trimethoxysilyl)- Silquest A 189 3-(Trimethoxysilyl)-1-Propanethiol Prosil 196 Silane A 189 (3-Thiopropyl)trimethoxysilane NUCA 189 3-(Sulfanylpropyl)trimethoxysilane M 8500 (coupling agent) 3-(Trimethoxysilyl)propyl mercaptan A 189 (silicone) KBE 803
Full Description

Mercaptopropyltrimethoxysilane (MPTMS) is an organosilane coupling agent with the molecular formula C6H16O3SSi that provides adhesion promotion and coupling functionality between organic and inorganic materials. This silane compound is utilized across agriculture, coatings & construction, industrial manufacturing, and plastics & polymers industries where enhanced interfacial bonding is required. The mercapto functional group enables strong chemical bonding to substrates while the trimethoxysilyl group provides hydrolyzable functionality for surface modification applications.